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Leptin Protects Host Cells from Entamoeba histolytica Cytotoxicity by a STAT3-Dependent Mechanism

The adipocytokine leptin links nutritional status to immune function. Leptin signaling protects from amebiasis, but the molecular mechanism is not understood. We developed an in vitro model of ameba-host cell interaction to test the hypothesis that leptin prevents ameba-induced apoptosis in host epi...

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Detalhes bibliográficos
Main Authors: Marie, Chelsea S., Verkerke, Hans P., Paul, Shom N., Mackey, Aaron J., Petri, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347425/
https://ncbi.nlm.nih.gov/pubmed/22331430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06140-11
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