Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes.

The transcription factor E2F is present in independent complexes with the product of the retinoblastoma susceptibility gene, pRB, and a related gene product, p107, in association with the cyclin A-cdk2 or the cyclin E-cdk2 kinase complex. pRB and p107 can negatively regulate E2F activity, since over...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Fattaey, A R, Harlow, E, Helin, K
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1993
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364797/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7267-7277.1993
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