Sensitive Cell-Based Assay for Determination of Human Immunodeficiency Virus Type 1 Coreceptor Tropism

CCR5 antagonists are a powerful new class of antiretroviral drugs that require a companion assay to evaluate the presence of CXCR4-tropic (non-R5) viruses prior to use in human immunodeficiency virus (HIV)-infected individuals. In this study, we have developed, characterized, verified, and prevalida...

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Detalhes bibliográficos
Main Authors: Weber, Jan, Vazquez, Ana C., Winner, Dane, Gibson, Richard M., Rhea, Ariel M., Rose, Justine D., Wylie, Doug, Henry, Kenneth, Wright, Alison, King, Kevin, Archer, John, Poveda, Eva, Soriano, Vicente, Robertson, David L., Olivo, Paul D., Arts, Eric J., Quiñones-Mateu, Miguel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647936/
https://ncbi.nlm.nih.gov/pubmed/23486708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00092-13
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