Use of Four Next-Generation Sequencing Platforms to Determine HIV-1 Coreceptor Tropism

HIV-1 coreceptor tropism assays are required to rule out the presence of CXCR4-tropic (non-R5) viruses prior treatment with CCR5 antagonists. Phenotypic (e.g., Trofile™, Monogram Biosciences) and genotypic (e.g., population sequencing linked to bioinformatic algorithms) assays are the most widely us...

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Autors principals: Archer, John, Weber, Jan, Henry, Kenneth, Winner, Dane, Gibson, Richard, Lee, Lawrence, Paxinos, Ellen, Arts, Eric J., Robertson, David L., Mimms, Larry, Quiñones-Mateu, Miguel E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498215/
https://ncbi.nlm.nih.gov/pubmed/23166726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049602
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