Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells.

Malignant astrocytoma is the most common primary human brain tumor. Most astrocytomas express a combination of platelet-derived growth factor (PDGF) and PDGF receptor which could close an autocrine loop. It is not known whether these autocrine loops contribute to the transformed phenotype of astrocy...

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Sonraí Bibleagrafaíochta
Main Authors: Shamah, S M, Stiles, C D, Guha, A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1993
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC364790/
https://ncbi.nlm.nih.gov/pubmed/8246942
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