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Dominant negative mutants of transforming growth factor-beta 1 inhibit the secretion of different transforming growth factor-beta isoforms.

Transforming growth factor-beta (TGF-beta) is a secreted polypeptide factor that is thought to play a major role in the regulation of proliferation of many cell types and various differentiation processes. Several related isoforms have been structurally characterized, three of which, TGF-beta 1, -be...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Lopez, A R, Cook, J, Deininger, P L, Derynck, R
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369610/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549120/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.4.1674
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