Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor.

Autophosphorylation sites of growth factor receptors with tyrosine kinase activity function as specific binding sites for Src homology 2 (SH2) domains of signaling molecules. This interaction appears to be a crucial step in a mechanism by which receptor tyrosine kinases relay signals to downstream s...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Nishimura, R, Li, W, Kashishian, A, Mondino, A, Zhou, M, Cooper, J, Schlessinger, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7692233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6889-6896.1993
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