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Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor.
Autophosphorylation sites of growth factor receptors with tyrosine kinase activity function as specific binding sites for Src homology 2 (SH2) domains of signaling molecules. This interaction appears to be a crucial step in a mechanism by which receptor tyrosine kinases relay signals to downstream s...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7692233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6889 |
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