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Targeting PI3K in Cancer: Any Good News?

The phosphatidylinositol 3-kinase (PI3K) signaling pathway regulates several cellular processes and it’s one of the most frequently deregulated pathway in human tumors. Given its prominent role in cancer, there is great interest in the development of inhibitors able to target several members of PI3K...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Martini, Miriam, Ciraolo, Elisa, Gulluni, Federico, Hirsch, Emilio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647219/
https://ncbi.nlm.nih.gov/pubmed/23658859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00108
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