A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs.

We have isolated cDNAs for four human genes (DPDE1 through DPDE4) closely related to the dnc learning and memory locus of Drosophila melanogaster. The deduced amino acid sequences of the Drosophila and human proteins have considerable homology, extending beyond the putative catalytic region to inclu...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

I whakaputaina i:	Mol Cell Biol
Ngā kaituhi matua:	Bolger, G, Michaeli, T, Martins, T, St John, T, Steiner, B, Rodgers, L, Riggs, M, Wigler, M, Ferguson, K
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Taylor & Francis 1993
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364715/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413254/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.10.6558-6571.1993
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!