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Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.
Loss of a functional retinoblastoma tumor suppressor gene product, pRB, is a key step in the development of many human tumors. pRB is a negative regulator of cell proliferation and appears to participate in control of entry into the S phase of the cell cycle. The recent demonstration that pRB binds...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1993
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413249/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.10.6501 |
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