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Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.

Loss of a functional retinoblastoma tumor suppressor gene product, pRB, is a key step in the development of many human tumors. pRB is a negative regulator of cell proliferation and appears to participate in control of entry into the S phase of the cell cycle. The recent demonstration that pRB binds...

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Bibliografske podrobnosti
Main Authors: Helin, K, Harlow, E, Fattaey, A
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC364709/
https://ncbi.nlm.nih.gov/pubmed/8413249
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