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The role of IL-15 in activating STAT5 and fine-tuning IL-17A production in CD4 T lymphocytes
Interleukin-15 (IL-15) is an important IL-2 related cytokine, whose role in Th17 cell biology has not been fully elucidated. Here we show that exogenous IL-15 decreased IL-17A production in Th17 cultures. Neutralizing IL-15 using an antibody led to increases in IL-17A production in Th17 cultures. Bo...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647038/ https://ncbi.nlm.nih.gov/pubmed/22993203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201476 |
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