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Proteostasis Modulators with Discriminating Taste
Small molecules that perturb protein homeostasis are used as cancer therapeutics and as antibiotics to treat bacterial infections. Kannan et al. (Cell 2012) describe an intriguing mechanism that enables ribosome-targeted macrolides to selectively remodel the bacterial proteome. This finding suggests...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647031/ https://ncbi.nlm.nih.gov/pubmed/23438743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.02.002 |
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