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Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1)
Aurora kinase B is a critical component of the chromosomal passenger complex, which is involved in the regulation of microtubule-kinetochore attachments and cytokinesis. By using conditional knockout cells and chemical inhibition, we show here that inactivation of Aurora B results in delayed G(1)/S...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646860/ https://ncbi.nlm.nih.gov/pubmed/23428904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24004 |
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