Loading...
Dissecting the pathways that destabilize mutant p53: The proteasome or autophagy?
One fundamental feature of mutant forms of p53 consists in their accumulation at high levels in tumors. At least in the case of neomorphic p53 mutations, which acquire oncogenic activity, stabilization is a driving force for tumor progression. It is well documented that p53 mutants are resistant to...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2013
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646859/ https://ncbi.nlm.nih.gov/pubmed/23466706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24128 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|