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FTY720/Fingolimod, a Sphingosine Analogue, Reduces Amyloid-β Production in Neurons
Sphingosine-1-phosphate (S1P) is a pluripotent lipophilic mediator working as a ligand for G-protein coupled S1P receptors (S1PR), which is currently highlighted as a therapeutic target for autoimmune diseases including relapsing forms of multiple sclerosis. Sphingosine related compounds, FTY720 and...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646787/ https://ncbi.nlm.nih.gov/pubmed/23667698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064050 |
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