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The Second Intracellular Loop of the Human Cannabinoid CB2 Receptor Governs G Protein Coupling in Coordination with the Carboxyl Terminal Domain

The major effects of cannabinoids and endocannabinoids are mediated via two G protein-coupled receptors, CB1 and CB2, elucidation of the mechanism and structural determinants of the CB2 receptor coupling with G proteins will have a significant impact on drug discovery. In the present study, we syste...

詳細記述

保存先:
書誌詳細
主要な著者: Zheng, Congxia, Chen, Linjie, Chen, Xiaopan, He, Xiaobai, Yang, Jingwen, Shi, Ying, Zhou, Naiming
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646771/
https://ncbi.nlm.nih.gov/pubmed/23667597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063262
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