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Distinct Second Extracellular Loop Structures of the Brain Cannabinoid CB(1) Receptor: Implication in Ligand Binding and Receptor Function
The G-protein coupled receptor (GPCR) second extracellular loop (E2) is known to play an important role in receptor structure and function. The brain cannabinoid (CB(1)) receptor is unique in that it lacks the inter-loop E2 disulfide linkage to the transmembrane (TM) helical bundle, a characteristic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058415/ https://ncbi.nlm.nih.gov/pubmed/21120862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22907 |
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