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Distinct Second Extracellular Loop Structures of the Brain Cannabinoid CB(1) Receptor: Implication in Ligand Binding and Receptor Function

The G-protein coupled receptor (GPCR) second extracellular loop (E2) is known to play an important role in receptor structure and function. The brain cannabinoid (CB(1)) receptor is unique in that it lacks the inter-loop E2 disulfide linkage to the transmembrane (TM) helical bundle, a characteristic...

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Hlavní autoři: Shim, Joong-Youn, Rudd, James, Ding, Tomas T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058415/
https://ncbi.nlm.nih.gov/pubmed/21120862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22907
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