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Distinct Second Extracellular Loop Structures of the Brain Cannabinoid CB(1) Receptor: Implication in Ligand Binding and Receptor Function

The G-protein coupled receptor (GPCR) second extracellular loop (E2) is known to play an important role in receptor structure and function. The brain cannabinoid (CB(1)) receptor is unique in that it lacks the inter-loop E2 disulfide linkage to the transmembrane (TM) helical bundle, a characteristic...

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Bibliografiske detaljer
Main Authors: Shim, Joong-Youn, Rudd, James, Ding, Tomas T.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058415/
https://ncbi.nlm.nih.gov/pubmed/21120862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22907
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