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Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?

The 118A>G single nucleotide polymorphism (SNP) in the μ-opioid receptor (OPRM1) gene has been the most described variant in pharmacogenetic studies regarding opioid drugs. Despite evidence for an altered biological function encoded by this variant, this knowledge is not yet utilized clinically....

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Dettagli Bibliografici
Autori principali: Mura, Elisa, Govoni, Stefano, Racchi, Marco, Carossa, Valeria, Ranzani, Guglielmina Nadia, Allegri, Massimo, van Schaik, Ron HN
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645947/
https://ncbi.nlm.nih.gov/pubmed/23658496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S42040
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