Clinical Application of Pharmacogenetics: Where are We Now?

Por van Schaik, Ron HN
Publicado no EJIFCC (2014)

6. Dose Adjustments Based on Pharmacogenetics of CYP450 Enzymes

Por van Schaik, Ron H.N.
Publicado no EJIFCC (2008)

A Guide to the Current Web-Based Resources in Pharmacogenomics

Por Glubb, Dylan M., Paugh, Steven W., van Schaik, Ron H.N., Innocenti, Federico
Publicado em 2013

A new CYP3A5 variant, CYP3A5*11, is shown to be defective in nifedipine metabolism in a recombinant cDNA expression system

Por Lee, Su-Jun, van der Heiden, Ilse P, Goldstein, Joyce A, van Schaik, Ron HN
Publicado em 2006

Time of injury affects urinary biomarker predictive values for acute kidney injury in critically ill, non-septic patients

Por de Geus, Hilde RH, Fortrie, Gijs, Betjes, Michiel GH, van Schaik, Ron HN, Groeneveld, AB Johan
Publicado em 2013

Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?

Por Mura, Elisa, Govoni, Stefano, Racchi, Marco, Carossa, Valeria, Ranzani, Guglielmina Nadia, Allegri, Massimo, van Schaik, Ron HN
Publicado em 2013

CYP2D6 genotype can help to predict effectiveness and safety during opioid treatment for chronic low back pain: results from a retrospective study in an Italian cohort

Por Dagostino, Concetta, Allegri, Massimo, Napolioni, Valerio, D’Agnelli, Simona, Bignami, Elena, Mutti, Antonio, van Schaik, Ron HN
Publicado no Pharmgenomics Pers Med (2018)

Genetic Variation in the Multidrug and Toxin Extrusion 1 Transporter Protein Influences the Glucose-Lowering Effect of Metformin in Patients With Diabetes: A Preliminary Study

Por Becker, Matthijs L., Visser, Loes E., van Schaik, Ron H.N., Hofman, Albert, Uitterlinden, André G., Stricker, Bruno H.Ch.
Publicado em 2009

Differences in CYP3A genotypes of a liver transplant recipient and the donor liver graft and adjustment of tacrolimus dose

Por Berger, Florine A., Mulder, Midas B., ten Bosch‐Dijksman, Willemijn, van Schaik, Ron H.N., Coenen, Sandra, de Winter, Brenda C.M.
Publicado no Br J Clin Pharmacol (2019)

CYP3A5, ABCB1 and SLCO1B1 Polymorphisms and Pharmacokinetics and Virologic Outcome of Lopinavir/Ritonavir in HIV-infected Children

Por Rakhmanina, Natella Y., Neely, Michael, Van Schaik, Ron H.N., Gordish-Dressman, Heather, Williams, Keetra D., Soldin, Steven J., van den Anker, John N.
Publicado em 2011

Global pharmacogenomics within precision medicine: challenges and opportunities

Por Chenoweth, Meghan J., Giacomini, Kathleen M., Pirmohamed, Munir, Hill, Susan L., van Schaik, Ron H.N., Schwab, Matthias, Shuldiner, Alan R., Relling, Mary V., Tyndale, Rachel F.
Publicado no Clin Pharmacol Ther (2019)

Hot flashes are not predictive for serum concentrations of tamoxifen and its metabolites

Por Jager, Nynke GL, Koornstra, Rutger HT, Vincent, Andrew D, van Schaik, Ron HN, Huitema, Alwin DR, Korse, Tiny M, Schellens, Jan HM, Linn, Sabine C, Beijnen, Jos H
Publicado em 2013

Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Starting Dose

Por Andrews, Louise M., de Winter, Brenda C.M., Tang, Jiang-Tao, Shuker, Nauras, Bouamar, Rachida, van Schaik, Ron H.N., Koch, Birgit C.P., van Gelder, Teun, Hesselink, Dennis A.
Publicado no Transplant Direct (2017)

Minimum information required for a DMET experiment reporting

Por Kumuthini, Judit, Mbiyavanga, Mamana, Chimusa, Emile R, Pathak, Jyotishman, Somervuo, Panu, Van Schaik, Ron HN, Dolzan, Vita, Mizzi, Clint, Kalideen, Kusha, Ramesar, Raj S, Macek, Milan, Patrinos, George P, Squassina, Alessio
Publicado no Pharmacogenomics (2016)

Monitoring the tacrolimus concentration in peripheral blood mononuclear cells of kidney transplant recipients

Por Francke, Marith I., Hesselink, Dennis A., Li, Yi, Koch, Birgit C.P., de Wit, Lucia E.A., van Schaik, Ron H.N., Yang, Lin, Baan, Carla C., van Gelder, Teun, de Winter, Brenda C.M.
Publicado no Br J Clin Pharmacol (2020)

Influence of Genetic Variation in COMT on Cisplatin-Induced Nephrotoxicity in Cancer Patients

Por Agema, Bram C., Koolen, Stijn L.W., de With, Mirjam, van Doorn, Nadia, Heersche, Niels, Oomen-de Hoop, Esther, Visser, Sabine, Aerts, Joachim G.J.V., Bins, Sander, van Schaik, Ron H.N., Mathijssen, Ron H.J.
Publicado no Genes (Basel) (2020)

Patients with NSCLC may display a low ratio of p.T790M vs. activating EGFR mutations in plasma at disease progression: implications for personalised treatment

Por Del Re, Marzia, Bordi, Paola, Petrini, Iacopo, Rofi, Eleonora, Mazzoni, Francesca, Belluomini, Lorenzo, Vasile, Enrico, Restante, Giuliana, Di Costanzo, Francesco, Falcone, Alfredo, Frassoldati, Antonio, van Schaik, Ron H.N., Steendam, Christi M.J., Chella, Antonio, Tiseo, Marcello, Morganti, Riccardo, Danesi, Romano
Publicado no Oncotarget (2017)

A Multi-Center Study of [−2]Pro-Prostate-Specific Antigen (PSA) in Combination with PSA and Free PSA for Prostate Cancer Detection in the 2.0 to 10.0 ng/mL PSA Range

Por Catalona, William J., Partin, Alan W., Sanda, Martin G., Wei, John T., Klee, George G., Bangma, Chris H., Slawin, Kevin M., Marks, Leonard S., Loeb, Stacy, Broyles, Dennis L., Shin, Sanghyuk S., Cruz, Amabelle B., Chan, Daniel W., Sokoll, Lori J., Roberts, William L., van Schaik, Ron H.N., Mizrahi, Isaac A.
Publicado em 2011

CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity

Por de Graan, Anne-Joy M., Elens, Laure, Sprowl, Jason A., Sparreboom, Alex, Friberg, Lena E., van der Holt, Bronno, de Raaf, Pleun J., de Bruijn, Peter, Engels, Frederike K., Eskens, Ferry A.L.M., Wiemer, Erik A.C., Verweij, Jaap, Mathijssen, Ron H.J., van Schaik, Ron H.N.
Publicado em 2013

Prospective, Multi-Center Evaluation of the Beckman Coulter Prostate Health Index Using WHO Calibration

Por Loeb, Stacy, Sokoll, Lori J., Broyles, Dennis L., Bangma, Chris H., van Schaik, Ron H.N., Klee, George G., Wei, John T., Sanda, Martin G., Partin, Alan W., Slawin, Kevin M., Marks, Leonard S., Mizrahi, Isaac A., Shin, Sanghyuk S., Cruz, Amabelle B., Chan, Daniel W., Roberts, William L., Catalona, William J.
Publicado no J Urol (2012)