Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.

The translocation (6;9)(p23;q34) in acute nonlymphocytic leukemia results in the formation of a highly consistent dek-can fusion gene. Translocation breakpoints invariably occur in single introns of dek and can, which were named icb-6 and icb-9, respectively. In a case of acute undifferentiated leuk...

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Vydáno v:Mol Cell Biol
Hlavní autoři: von Lindern, M, van Baal, S, Wiegant, J, Raap, A, Hagemeijer, A, Grosveld, G
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364582/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1630450/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.8.3346
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