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Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.

The translocation (6;9)(p23;q34) in acute nonlymphocytic leukemia results in the formation of a highly consistent dek-can fusion gene. Translocation breakpoints invariably occur in single introns of dek and can, which were named icb-6 and icb-9, respectively. In a case of acute undifferentiated leuk...

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Bibliografiske detaljer
Main Authors: von Lindern, M, van Baal, S, Wiegant, J, Raap, A, Hagemeijer, A, Grosveld, G
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC364582/
https://ncbi.nlm.nih.gov/pubmed/1630450
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