Physical and genetic-interaction density reveals functional organization and informs significance cutoffs in genome-wide screens

Genome-wide experiments often measure quantitative differences between treated and untreated cells to identify affected strains. For these studies, statistical models are typically used to determine significance cutoffs. We developed a method termed “CLIK” (Cutoff Linked to Interaction Knowledge) th...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Dittmar, John C., Pierce, Steven, Rothstein, Rodney, Reid, Robert J. D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645594/
https://ncbi.nlm.nih.gov/pubmed/23589890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219582110
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller