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Physical and genetic-interaction density reveals functional organization and informs significance cutoffs in genome-wide screens
Genome-wide experiments often measure quantitative differences between treated and untreated cells to identify affected strains. For these studies, statistical models are typically used to determine significance cutoffs. We developed a method termed “CLIK” (Cutoff Linked to Interaction Knowledge) th...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645594/ https://ncbi.nlm.nih.gov/pubmed/23589890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219582110 |
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