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Genome-Wide Analysis of Rad52 Foci Reveals Diverse Mechanisms Impacting Recombination

To investigate the DNA damage response, we undertook a genome-wide study in Saccharomyces cerevisiae and identified 86 gene deletions that lead to increased levels of spontaneous Rad52 foci in proliferating diploid cells. More than half of the genes are conserved across species ranging from yeast to...

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Detalhes bibliográficos
Main Authors: Alvaro, David, Lisby, Michael, Rothstein, Rodney
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134942/
https://ncbi.nlm.nih.gov/pubmed/18085829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030228
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