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Genome-Wide Analysis of Rad52 Foci Reveals Diverse Mechanisms Impacting Recombination

To investigate the DNA damage response, we undertook a genome-wide study in Saccharomyces cerevisiae and identified 86 gene deletions that lead to increased levels of spontaneous Rad52 foci in proliferating diploid cells. More than half of the genes are conserved across species ranging from yeast to...

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Détails bibliographiques
Auteurs principaux: Alvaro, David, Lisby, Michael, Rothstein, Rodney
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134942/
https://ncbi.nlm.nih.gov/pubmed/18085829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030228
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