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Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions
Srs2 is a 3’ to 5’ DNA helicase that regulates many aspects of DNA metabolism in Saccharomyces cerevisiae. It is best known for its ability to counteract homologous recombination by dismantling Rad51 filaments, but is also involved in checkpoint activation, adaptation and recovery, and in resolution...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084345/ https://ncbi.nlm.nih.gov/pubmed/21459050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.02.004 |
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