Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase.

Maturation of most eukaryotic mRNA 3' ends requires endonucleolytic cleavage and polyadenylation of precursor mRNAs. To further understand the mechanism and function of mRNA 3' end processing, we identified a temperature-sensitive mutant of Saccharomyces cerevisiae defective for polyadenylation. Gen...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Patel, D, Butler, J S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620131/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.7.3297-3304.1992
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