Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase.
Maturation of most eukaryotic mRNA 3' ends requires endonucleolytic cleavage and polyadenylation of precursor mRNAs. To further understand the mechanism and function of mRNA 3' end processing, we identified a temperature-sensitive mutant of Saccharomyces cerevisiae defective for polyadenylation. Gen...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620131/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.7.3297-3304.1992 |
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