Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase.

Maturation of most eukaryotic mRNA 3' ends requires endonucleolytic cleavage and polyadenylation of precursor mRNAs. To further understand the mechanism and function of mRNA 3' end processing, we identified a temperature-sensitive mutant of Saccharomyces cerevisiae defective for polyadenylation. Gen...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Patel, D, Butler, J S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620131/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.7.3297-3304.1992
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