Deferiprone Reduces Amyloid-β and Tau Phosphorylation Levels but not Reactive Oxygen Species Generation in Hippocampus of Rabbits Fed a Cholesterol-Enriched Diet

Accumulation of amyloid-β (Aβ) peptide and the hyperphosphorylation of tau protein are major hallmarks of Alzheimer’s disease (AD). The causes of AD are not well known but a number of environmental and dietary factors are suggested to increase the risk of developing AD. Additionally, altered metabol...

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Main Authors: Prasanthi, Jaya R.P., Schrag, Matthew, Dasari, Bhanu, Marwarha, Gurdeep, Kirsch, Wolff M., Ghribi, Othman
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645354/
https://ncbi.nlm.nih.gov/pubmed/22406440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-111346
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