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Caffeine protects against oxidative stress and Alzheimer’s disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet

Cholesterol has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD) as a risk factor increasing β-amyloid (Aβ) and oxidative stress levels. Caffeine has anti-oxidant properties and has been demonstrated to reduce Aβ levels in transgenic mouse models of familial AD. However, the effe...

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Autori principali: Prasanthi, Jaya R.P., Dasari, Bhanu, Marwarha, Gurdeep, Larson, Tyler, Chen, Xuesong, Geiger, Jonathan D., Ghribi, Othman
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930139/
https://ncbi.nlm.nih.gov/pubmed/20638472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.07.007
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