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Caffeine protects against oxidative stress and Alzheimer’s disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet
Cholesterol has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD) as a risk factor increasing β-amyloid (Aβ) and oxidative stress levels. Caffeine has anti-oxidant properties and has been demonstrated to reduce Aβ levels in transgenic mouse models of familial AD. However, the effe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930139/ https://ncbi.nlm.nih.gov/pubmed/20638472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.07.007 |
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