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Molecular structure and evolution of double-minute chromosomes in methotrexate-resistant cultured mouse cells.
To determine whether microscopically visible double-minute chromosomes (DMs) are derived from submicroscopic precursors, we monitored the amplification of the dihydrofolate reductase (DHFR) gene in 10 independent isolates of methotrexate (MTX)-resistant mouse cells. At every other doubling in MTX co...
Gorde:
| Argitaratua izan da: | Mol Cell Biol |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Taylor & Francis
1992
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1620104/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.7.2911 |
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