Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene.

Drug resistance is a major impediment to the effective treatment of parasitic diseases. The role of multidrug resistance (mdr) genes and their products in this drug resistance phenomenon, however, remains controversial. In order to determine whether mdr gene amplification and overexpression can be c...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Henderson, D M, Sifri, C D, Rodgers, M, Wirth, D F, Hendrickson, N, Ullman, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364480/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1350325/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2855-2865.1992
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