D,L-alpha-difluoromethylornithine inhibits human cytomegalovirus replication.
D,L-alpha-Difluoromethylornithine (DFMO) is an inhibitor of ornithine decarboxylase, the first enzyme in the polyamine biosynthetic pathway. Exposure of human foreskin fibroblast cells to DFMO before their infection with human strains of cytomegalovirus (CMV) resulted in a reduction in the amount of...
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| Udgivet i: | J Virol |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1984
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6321786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.50.1.145-154.1984 |
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