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D,L-alpha-difluoromethylornithine inhibits human cytomegalovirus replication.

D,L-alpha-Difluoromethylornithine (DFMO) is an inhibitor of ornithine decarboxylase, the first enzyme in the polyamine biosynthetic pathway. Exposure of human foreskin fibroblast cells to DFMO before their infection with human strains of cytomegalovirus (CMV) resulted in a reduction in the amount of...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Gibson, W, van Breemen, R, Fields, A, LaFemina, R, Irmiere, A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1984
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255594/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6321786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.50.1.145-154.1984
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