D,L-alpha-difluoromethylornithine inhibits human cytomegalovirus replication.

D,L-alpha-Difluoromethylornithine (DFMO) is an inhibitor of ornithine decarboxylase, the first enzyme in the polyamine biosynthetic pathway. Exposure of human foreskin fibroblast cells to DFMO before their infection with human strains of cytomegalovirus (CMV) resulted in a reduction in the amount of...

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Argitaratua izan da:	J Virol
Egile Nagusiak:	Gibson, W, van Breemen, R, Fields, A, LaFemina, R, Irmiere, A
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1984
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6321786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.50.1.145-154.1984
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