GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.

Ítems similars

• Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase.
  per: Kazlauskas, A, et al.
  Publicat: (1990)
• In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase.
  per: Cooper, J A, et al.
  Publicat: (1993)
• The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1.
  per: Valius, M, et al.
  Publicat: (1995)
• Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively.
  per: Valius, M, et al.
  Publicat: (1993)
• Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity.
  per: Klinghoffer, R A, et al.
  Publicat: (1996)