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Deficiency of phospholipase A(2) group 7 decreases intestinal polyposis and colon tumorigenesis in Apc (Min/+) mice

Platelet-activating factor (PAF) is a naturally occurring phospholipid that mediates diverse effects such as physiological and pathological inflammation, immunosuppression, and cancer. Several lines of evidence support both positive and negative roles for PAF in carcinogenesis. PAF stimulates cell g...

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Bibliographic Details
Main Authors: Xu, Changxin, Reichert, Ethan C., Nakano, Tomoyuki, Lohse, Mariah, Gardner, Alison A., Revelo, Mónica P., Topham, Matthew K., Stafforini, Diana M.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643996/
https://ncbi.nlm.nih.gov/pubmed/23361301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2374
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