Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis
Although nonsteroidal antiinflammatory drugs (NSAIDs) show great promise as therapies for colon cancer, a dispute remains regarding their mechanism of action. NSAIDs are known to inhibit cyclooxygenase (COX) enzymes, which convert arachidonic acid (AA) to prostaglandins (PGs). Therefore, NSAIDs may...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31157/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051635898 |
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