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Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis
Although nonsteroidal antiinflammatory drugs (NSAIDs) show great promise as therapies for colon cancer, a dispute remains regarding their mechanism of action. NSAIDs are known to inhibit cyclooxygenase (COX) enzymes, which convert arachidonic acid (AA) to prostaglandins (PGs). Therefore, NSAIDs may...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31157/ https://ncbi.nlm.nih.gov/pubmed/11274413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051635898 |
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