The HIP1 initiator element plays a role in determining the in vitro requirement of the dihydrofolate reductase gene promoter for the C-terminal domain of RNA polymerase II.

We examined the ability of purified RNA polymerase (RNAP) II lacking the carboxy-terminal heptapeptide repeat domain (CTD), called RNAP IIB, to transcribe a variety of promoters in HeLa extracts in which endogenous RNAP II activity was inhibited with anti-CTD monoclonal antibodies. Not all promoters...

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Autores principales: Buermeyer, A B, Thompson, N E, Strasheim, L A, Burgess, R R, Farnham, P J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC364397/
https://ncbi.nlm.nih.gov/pubmed/1569952
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