The HIP1 initiator element plays a role in determining the in vitro requirement of the dihydrofolate reductase gene promoter for the C-terminal domain of RNA polymerase II.

We examined the ability of purified RNA polymerase (RNAP) II lacking the carboxy-terminal heptapeptide repeat domain (CTD), called RNAP IIB, to transcribe a variety of promoters in HeLa extracts in which endogenous RNAP II activity was inhibited with anti-CTD monoclonal antibodies. Not all promoters...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Buermeyer, A B, Thompson, N E, Strasheim, L A, Burgess, R R, Farnham, P J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569952/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.2250
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