Mechanism of action of a repressor of dioxin-dependent induction of Cyp1a1 gene transcription.

A dominant mutant of Hepa-1 cells, c31, expresses a repressor that prevents 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-dependent stimulation of Cyp1a1 transcription. The repressor acts via the xenobiotic-responsive elements (XREs), which are the DNA-binding sites for the aryl hydrocarbon (Ah) recept...

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Publicat a:	Mol Cell Biol
Autors principals:	Watson, A J, Weir-Brown, K I, Bannister, R M, Chu, F F, Reisz-Porszasz, S, Fujii-Kuriyama, Y, Sogawa, K, Hankinson, O
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364383/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1314949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.2115-2123.1992
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