Combined transfection of Bcl-2 siRNA and miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells

OBJECTIVE: B-cell lymphoma 2 (Bcl-2) is an important member of the Bcl-2 family of proteins that regulate the induction of apoptosis. This study aims to investigate whether Bcl-2 small interfering RNA (siRNA) combined with miR-15a oligonucleotides (ODN) could enhance methotrexate (MTX)-induced apopt...

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Detalhes bibliográficos
Main Authors: Ding, Li, Hu, Xiao-Mao, Wu, Hong, Liu, Ge-Xiu, Gao, Yang-Jun, He, Dong-Mei, Zhang, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Chinese Anti-Cancer Association 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643686/
https://ncbi.nlm.nih.gov/pubmed/23691440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7497/j.issn.2095-3941.2013.01.003
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