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Position is the critical determinant for function of iron-responsive elements as translational regulators.

At least two groups of eukaryotic mRNAs (ferritin and erythroid 5-aminolevulinate synthase) are translationally regulated via iron-responsive elements (IREs) located in a conserved position within the 5' untranslated regions of their mRNAs. We establish that the spacing between the 5' term...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Goossen, B, Hentze, M W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.1959
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