Position is the critical determinant for function of iron-responsive elements as translational regulators.

At least two groups of eukaryotic mRNAs (ferritin and erythroid 5-aminolevulinate synthase) are translationally regulated via iron-responsive elements (IREs) located in a conserved position within the 5' untranslated regions of their mRNAs. We establish that the spacing between the 5' term...

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Bibliographic Details
Main Authors: Goossen, B, Hentze, M W
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC364366/
https://ncbi.nlm.nih.gov/pubmed/1569933
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