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Only two of the five zinc fingers of the eukaryotic transcriptional repressor PRDI-BF1 are required for sequence-specific DNA binding.

The eukaryotic transcriptional repressor PRDI-BF1 contains five zinc fingers of the C2H2 type, and the protein binds specifically to PRDI, a 14-bp regulatory element of the beta interferon gene promoter. We have investigated the amino acid sequence requirements for specific binding to PRDI and found...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Keller, A D, Maniatis, T
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364364/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.1940-1949.1992
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