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Only two of the five zinc fingers of the eukaryotic transcriptional repressor PRDI-BF1 are required for sequence-specific DNA binding.

The eukaryotic transcriptional repressor PRDI-BF1 contains five zinc fingers of the C2H2 type, and the protein binds specifically to PRDI, a 14-bp regulatory element of the beta interferon gene promoter. We have investigated the amino acid sequence requirements for specific binding to PRDI and found...

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Publicat a:Mol Cell Biol
Autors principals: Keller, A D, Maniatis, T
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364364/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1569931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.5.1940-1949.1992
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