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Leucine-specific domain modulates the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase

The leucine-specific domain (LSD) is a compact well-ordered module that participates in positioning of the conserved KMSKS catalytic loop in most leucyl-tRNA synthetases (LeuRSs). However, the LeuRS from Mycoplasma mobile (MmLeuRS) has a tetrapeptide GKDG instead of the LSD. Here, we show that the t...

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Bibliografiske detaljer
Main Authors: Yan, Wei, Tan, Min, Eriani, Gilbert, Wang, En-Duo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643597/
https://ncbi.nlm.nih.gov/pubmed/23525458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt185
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