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CFTR Inhibitors for Treating Diarrheal Disease
Secretory diarrhea remains a major health challenge worldwide. Excessive fluid secretion in the intestine caused by enterotoxins results in activation of luminal Cl(−) channels on enterocytes. The cystic fibrosis transmembrane conductance regulator (CFTR) protein is the major cyclic adenosine monoph...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643514/ https://ncbi.nlm.nih.gov/pubmed/22850599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.114 |
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