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NK cell tolerance of self-specific activating receptor KIR2DS1 in individuals with cognate HLA-C2 ligand
NK cells are regulated by inhibiting and activating cell surface receptors. Most inhibitory receptors recognize MHC-class I antigens, and protect healthy cells from NK cell-mediated auto-aggression. However, certain activating receptors, including the human killer cell Ig-like receptor (KIR) 2DS1, a...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643210/ https://ncbi.nlm.nih.gov/pubmed/23554313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202120 |
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