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Heptamethine Cyanine Based (64)Cu - PET Probe PC-1001 for Cancer Imaging: Synthesis and In Vivo Evaluation

PURPOSE: Development of a heptamethine cyanine based tumor-targeting PET imaging probe for noninvasive detection and diagnosis of breast cancer. METHODS: Tumor-specific heptamethine-cyanine DOTA conjugate complexed with Cu-64 (PC-1001) was synthesized for breast cancer imaging. In vitro cellular upt...

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Detalhes bibliográficos
Main Authors: Xiao, Li, Zhang, Yi, Yue, Wei, Xie, Xiuzhen, Wang, Ji-ping, Chordia, Mahendra D., Chung, Leland W.K., Pan, Dongfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643142/
https://ncbi.nlm.nih.gov/pubmed/23375364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2013.01.001
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