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A Novel Neutrophil-Specific PET Imaging Agent: cFLFLFK-PEG-(64)Cu

The synthesis and validation of a new, highly potent (64)Cu-labeled peptide, cFLFLFK-PEG-(64)Cu, that targets the formyl peptide receptor (FPR) on leukocytes is described. The peptide ligand is an antagonist of the FPR, designed not to elicit a chemotactic response resulting in neutropenia. Evidence...

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Hlavní autoři: Locke, Landon W., Chordia, Mahendra D., Zhang, Yi, Kundu, Bijoy, Kennedy, Dylan, Landseadel, Jessica, Xiao, Li, Fairchild, Karen D., Berr, Stuart S., Linden, Joel, Pan, Dongfeng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004780/
https://ncbi.nlm.nih.gov/pubmed/19372473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.056127
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